Prognostic and Diagnostic role of HE4 as a biomarker in ovarian cancer & comparison with CA125 in ovarian cancer patients with their menopausal status
نویسندگان
چکیده
Aim: to evaluate a new tumour marker HE4, in comparison with CA 125 and the Risk of Ovarian cancer pre postmenopausal women ovarian cancer.Method: The female patients were recruited from OPD/IPD Surgery Oncology department SMS Hospital, evaluated serum human epididymis protein (HE4) CA125 Patients divided into two group’s premenopausal cancer.Results: Serum HE4 level significantly high as compared cancer. result was high. (p
منابع مشابه
Evaluation of diagnostic accuracy of RMI and ROMA indices in comparison to HE4 and CA125 parameters for estimating the risk of malignancy of adnexal masses.
Background: Ovarian cancer is the fifth leading cancer-related cause of death in women worldwide and is often diagnosed at advanced stages. Regarding the low sensitivity and specificity of the currently available diagnostic techniques, in the present study, we aimed to evaluate the accuracy of RMI and ROMA indexes and comparing these two indexes with CA-125 and HE4 parameters for the diagnosis ...
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چکیده ندارد.
Correlation of Preoperative HE-4 and CA125 with Ovarian Cancer Staging in Ahvaz Imam Khomeni Hospital
Background: Given that ovarian cancer symptoms are nonspecific and that appropriate surgical staging and pathological grading are important for the best treatment and prognosis of patients, this study aimed to determine the correlation of preoperative serum levels of CA125 and He4 with staging and grading. Materials and Methods: This cross-sectional study recruited 29 patients with epithelial...
متن کاملCA125 in ovarian cancer.
A quarter of a century since its discovery, circulating CA125 antigen is recommended for clinical use in the USA for ovarian cancer screening of high-risk women with ovaries, despite its limited sensitivity and specificity. Recent findings suggest that CA125 might also serve as a predictive marker for pre-invasive ovarian carcinoma. Methods to quantify circulating CA125 evolved toward sensitive...
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ژورنال
عنوان ژورنال: International journal of advanced biochemistry research
سال: 2022
ISSN: ['2617-4693', '2617-4707']
DOI: https://doi.org/10.33545/26174693.2022.v6.i2a.137